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Biochemistry and Molecular Exercise Physiology Laboratory

The research program in the Biochemistry and Molecular Exercise Physiology Laboratory focuses on 1) advancing knowledge of underlying mechanisms on the loss of muscle mass and strength during aging (i.e., sarcopenia) and other catabolic conditions (e.g., cancer cachexia, muscle-disuse) and 2) developing the countermeasure strategies (exercise/dietary interventions) to counteract muscle wasting under various catabolic conditions. Particularly, the primary research interests in our lab include: 1) the role of oxidative stress and inflammation in skeletal muscle under various catabolic conditions, 2) the local and systemic adaptations to exercise and nutritional interventions in skeletal muscle, and 3) the effects of exercise and nutritional supplements on body composition and physical function. Our research aims to advance scientific knowledge through translational research, providing meaningful findings for future human health-related investigations.

Equipment List 

  • CFX Opus 96 Real-Time PCR System
  • T100 Thermal Cycler
  • Chemidoc touch Imaging System
  • Trans-Blot Turbo Transfer System
  • Invitrogen Powerease touch Wetsern blot system
  • Countess 3 Automated Cell Counter
  • Glomax Explorer multimodal plate reader
  • Nanodrop One-c spectrophotometer
  • Leica Inverted Microspcope with FlexCam Camera system
  • Accuspin Refrigerated microcentrifuge
  • Sorvall Legend XTR Refrigerated centrifuge
  • Megafige 8R Refrigerated centrifuge
  • 2.5 liter Freeze Dryer
  • Plate Washer
  • Epoch Plate Reader
  • 24.2 Cu. Ft. ULT -80 Freezer
  •  HM525 NX Crostat
  • Forma Series 3 CO2 incubator
  • Logic+ biosafety cabinet
  • Premier Chemical Fume Hood
  • Elite Benchtop Autoclave
  • Plate Rocker
  • Scale
  • 2 in one water bath
  • Jitterbug Plate Shaker
  • Heating Block
  • Heated Stirir
  • Tissue Homogenizer
  • Cell Sorter
  • Flourescent microscope
  • Cryostat
  • Surgical Suites
  • Animal Cages with advanced cage wash and bedding system
  • Biorad figital droplet PCR machine
  • H-7650 120kV Automatic transmission electron microscope with integrated CCD camera
  • S-3400N Variable Pressure scanning electron microscope
  • TM-1000 Tabletop scanning electron microscope
  • TCS SP5 II confocal microscope with a resonant scanner, 5-channel spectral detector, AOBS, with laser lines (all with AOTFs):  405, 488, 561, 594, and 633 nm
  • M165FC Fluorescence stereo microscope
  • Andor Dragonfly confocal system, 6 laser lines (405, 445, 488, 514, 568, 637)
  • Stage top microscope incubator (for imaging at mammalian physiological- and subambient temperatures)
  • ExCite wide field LED epifluorescence light source